The principal cytochrome P450 isoenzyme involved seems for being CYP2E1, with CYP1A2 and CYP3A4 as additional pathways. Close to eighty five% of the oral dose appears during the urine within just 24 hours of administration, most given that the glucuronide conjugate, with compact quantities of other conjugates and unchanged drug. https://josephm642mtw6.wikigiogio.com/user