Conolidine’s analgesic effects stem from its interaction with non-opioid pain pathways. As opposed to opioids, which bind to µ-opioid receptors during the central nervous technique, conolidine modulates alternate molecular targets. A Science Innovations review found that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. https://conolidine-nature-s-morph35678.creacionblog.com/38074402/5-simple-statements-about-conolidin-to-replace-traditional-painkillers-explained