This serves to be a germinal centre survival signal for autoreactive B-cells. Following migration in the mantle zone, autoreactive B cells demand further more survival signals from autoreactive helper T cells, which promote the maturation of autoantibody-generating plasma cells and B memory cells. Instruct patients with SLE in order https://charliecwsrv.look4blog.com/76394661/not-known-factual-statements-about-lupus-signs