Methotrexate: Providers sometimes recommend this medication for severe cases. It may cause liver disease. If you take it, your provider will monitor you with blood tests. Join a support group or visit a mental health provider. Psoriasis can affect a person’s mental health, increasing the risk of anxiety and depression. http://jaspercvmcr.total-blog.com/psoriase-uma-vis-o-geral-31312187